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Award Information
Proposal Number: 0912003
Proposal Title: Customized STR Typing System for Kinship Analysis
Topic Number: H-SB09.1-001
Phase: Phase II
Topic Title: Low-Cost and Rapid DNA-based Biometric Device
Organization: NetBio, Inc.
Address: 830 Winter Street
Waltham, MA 02451-1477  
Abstract: First described in the early 1990`s, short tandem repeat (STR) analysis is the gold standard of human identification. With a false identification rate as low as one in hundreds of trillions, STR analysis is a powerful tool for determining human identification objectively. The goal of this work is to improve the ability to evaluate kinship based on STR analyses. By creating an STR assay system that allows more accurate determination of kinship, DHS responsibilities such as granting asylum, processing applications for relatives to come to the US, and deterring child trafficking and illegal adoptions can be enhanced significantly. Current STR assays are highly effective for determining the likelihood of first degree relationships (parent-child and sibling-sibling) but are less effective at more distant relationships. By increasing the number of STR loci tested in a given assay, more distant relationships can be determined. The proposed work would result in such an improved assay, building on NetBio`s experience in designing systems that rapidly process nucleic acids without human intervention. It is hoped that this technology will improve the safety of society in general, and protect some of the most vulnerable members of our society in particular.
Award/Contract Number: N10PC20105
Period of Performance: 04/21/2010 - 04/20/2012
Award/Contract Value: $750,000.00
Award/Obligated Amount: $750,000.00