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Awards

Topic Information Award/Contract Number Proposal Information Company Performance
Period
Award/Contract
Value
Abstract

H-SB09.1-001
Low-Cost and Rapid DNA-based Biometric Device

NBCHC090035 0911079
(FY09.1 Phase I)
Low-cost and Rapid DNA Sequencer for Biometric Applications

Advanced Liquid Logic, Inc.
615 Davis Drive, Suite 800
PO Box 14025
Research Triangle Park, NC 27709-3169

05/15/2009
to
11/30/2009
$99,156.00

A DNA sequencer for biometric applications will be developed. The system will enable rapid and low-cost identification of individuals and kinship verification using a self-contained and portable device. All process steps from DNA extraction to DNA sequencing will be automatically performed within the disposable single-use cartridge. This high-level of functional integration is made possible by Advanced Liquid Logic`s digital microfluidic technology which enables precise manipulation of liquid droplets using an array of electrodes formed on an inexpensive printed-circuit-board (PCB). The goals of the Phase I project are to develop detailed use cases and product requirements, identify key technical risks and required research activities and to develop a system architecture and preliminary design.

H-SB09.1-001
Low-Cost and Rapid DNA-based Biometric Device

N10PC20104 0912007
(FY09.1 Phase II)
Low-cost and Rapid DNA Sequencer for Biometric Applications

Advanced Liquid Logic, Inc.
615 Davis Drive, Suite 800
PO Box 14025
Research Triangle Park, NC 27709-3169

08/04/2010
to
08/03/2012
$741,920.00

Advanced Liquid Logic proposes to develop a low-cost and rapid biometric system based on DNA. Using a miniaturized DNA sequencing format the device will enable DNA-based identification of individuals as well as determination of family relationships (kinship) between individuals. The system will be implemented using Advanced Liquid Logic`s proprietary Digital Microfluidics technology, which is based on the use of electrical fields to precisely and programmably manipulate liquid droplets within a self-contained cartridge. Complex analytical procedures can be flexibly implemented as a sequence of computer-controlled droplet operations without the use of pumps or valves. Both the instrument and the disposable cartridge can be made extremely inexpensively to provide a low cost per test with minimal infrastructural investment. In the Phase I project Advanced Liquid Logic was tasked with developing detailed product requirements, evaluating the proposed technological approach and performing preliminary design and conception of the proposed product. Based on the Phase I studies, a Phase II project is proposed in which a working prototype will be delivered for evaluation by DHS. Following completion of the Phase II project a Phase III product development effort will be launched to deliver a commercial rapid DNA testing product that meets DHS`s requirements.