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Awards

Topic Information Award/Contract Number Proposal Information Company Performance
Period
Award/Contract
Value
Abstract

H-SB06.1-001
AEROSOL COLLECTION INTO LOW ANALYSIS VOLUMES (ACLAV)

NBCHC060091 0611201
(FY06.1 Phase I)
Novel Electrostatics-based Sampler for Bioaerosol Collection in Small Analysis Volumes

CFD Research Corporation
215 Wynn Dr.
5th Floor
Huntsville, AL 35805-1926

09/01/2006
to
03/15/2007
$99,918.00

Current bioaerosol monitoring and evaluation systems are largely based on collection of airborne pathogens in a liquid medium, followed by the detection of the targets of interest. While available aerosol collection technologies employ large collection volumes, biosensors are capable of processing only a small fraction of the collection volume. Our overall objective is to design and demonstrate a novel electrostatics-based sampler that is capable of directly capturing the incoming stream of aerosol particles in very small collection volumes. This reduced collection volume provides multiple benefits including greater assay sensitivity, reduced probabilities of false negatives and reduction in overall logistical burden. Building on CFDRC's proven electrostatic collection technology, we will demonstrate aerosol collection in a small volume of collection buffer. Our main challenge is to increase throughput to 100 L/min while maintaining high efficiencies and minimizing losses. During Phase I, collection, concentration and capture efficiencies factors will be clearly demonstrated, using a judicious combination of computer-aided design/analysis and experimental testing with BSL-1 organisms. Phase II will focus on prototype integration and testing with an extensive set of class-based simulants and agents. An inter-disciplinary team has been assembled to ensure project success.