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Abstracts of FY05.1 Phase II Awards

H-SB05.1-001

Company

Core MicroSolutions Inc.
1100 Glendon Avenue 17th Floor
Los Angeles, CA 90024-3588

Proposal Information 0512001 - "Channel to Droplet Sample Extraction Analysis (SEA) Cartridge for Food Testing and Homeland Security Applications"
Topic Information H-SB05.1-001 - ADVANCED SAMPLE PROCESSING OF LIQUID, OR SOLID OR AEROSOL SAMPLES, OR A COMBINATION OF TWO OR THREE
Award/Contract Number NBCHC060082
Abstract

In Phase I R&D, Core Microsolutions (CMSS) and Professor Sung Cho of the University of Pittsburgh successfully demonstrated advanced "channel-to-droplet" sample concentration and extraction functions on a compact glass chip that integrated state of the art Electrowetting-on-Dielectric (EWOD) droplet handling and purification capabilties with well proven channel-based separation methods. The novel process first separated sample particles within a microchannel, then extracted the concentrated particles from a channel opening in droplet form, and lastly bifurcated the particle mix within the droplet using Dielectrophoretic separation methods for a 2nd degree of concentration. This proposed Phase II work will optimize the "channel-to-droplet" sample extraction concepts demonstrated in Phase I to develop a programmable and user-ready microfluidic cartridge that can concentrate and extract bacterial pathogens from dilute analyte solutions for food testing and Homeland Security applications. Battelle Memorial Institute has been subcontracted to package the CMSS designed microfluidic chips in a rugged, plug-and-play cartridge that will be evaluated using E. Coli, Listeria and Yersinia pestis samples. This disposable and compact Sample Extraction Analysis (SEA) cartridge will output concentrated sample droplets to reduce detection times and uncertainty, while offering programmable droplet delivery and user-selected antibody capture sites to maximize market appeal.

Company

CFD Research Corporation
215 Wynn Dr.
5th Floor
Huntsville, AL 35805-1926

Proposal Information 0512016 - A Novel Electrokinetics-Driven, Integrated Microfluidic Cartridge for Sample Preparation from Complex Matrices
Topic Information H-SB05.1-001 - ADVANCED SAMPLE PROCESSING OF LIQUID, OR SOLID OR AEROSOL SAMPLES, OR A COMBINATION OF TWO OR THREE
Award/Contract Number D06PC75222 (formerly NBCHC060070)
Abstract

Sample preparation has been recognized as the single most important challenge to be faced in the development of detect-to-warn (DTW) systems (NRC, 2005). Available commercial sample preparation technologies are expensive, slow (30 min to 2 hours) and require trained laboratory technicians for operation. Addressing this need, we propose to design, fabricate, demonstrate, and validate a novel integrated microfluidic cartridge exploiting advanced electrokinetics for preparation of complex liquid samples for genomic analysis. The Phase I study successfully demonstrated three critical elements: (1) sorting of bacterial cells (2) electric field driven microbial lysis, and (3) DNA capture and elution in a microfluidic extraction chamber. Physical prototypes of the components were fabricated and experimentally demonstrated. During Phase II, these components will be optimized and integrated along with a novel pre-concentrator to develop an integrated microfluidics sample preparation card. The integrated cartridge will be validated in challenge situations mixing simulants and threat agents with real-world contaminants. Proprietary design tools will be used to guide component development and layout optimization. An experienced, multi-disciplinary team with expertise in microfluidics engineering, microfabrication, and agent testing has been assembled.

H-SB05.1-002

Company

Radiation Monitoring Devices, Inc.
44 Hunt Street
Watertown, MA 02472-4699

Proposal Information 0512007 - IMPROVED SPECTROSCOPIC GAMMA RAY DETECTORS
Topic Information H-SB05.1-002 - IMPROVED SPECTROSCOPIC GAMMA RAY DETECTORS
Award/Contract Number NBCHC070018
Abstract

Spread of the weapons of mass destruction such as nuclear weapons is a serious threat in the world today. Prevention of the spread of radioactive materials and nuclear weapons has reached a state of heightened urgency in recent years, especially since the events of September 11, 2001 and its aftermath. Gamma ray spectrometers are an important tool in homeland defense and monitoring to check the spread of special nuclear materials (such as highly enriched uranium and weapons grade plutonium) and nuclear weapons. An important challenge in homeland security monitoring is not only to detect hidden radioactive materials but also to distinguish them from routinely used radiopharmaceuticals as well as naturally radioactive materials. The goal of the proposed effort is to investigate promising new scintillators for homeland security applications.

H-SB05.1-003

Company

Creare LLC
P.O. Box 71,
16 Great Hollow Road
Hanover, NH 03755-0071

Proposal Information 0512010 - Miniature, Efficient, Low-Vibration Cryocooler for Gamma Ray Detectors
Topic Information H-SB05.1-003 - IMPROVED HIGH PURITY GERMANIUM COOLING MECHANISMS
Award/Contract Number NBCHC060069
Abstract

Hand-held gamma ray spectrometers are a vital tool for detecting and identifying nuclear materials to counter the threat of radiological and nuclear terrorism. The High Purity Germanium crystals in these detectors must operate at cryogenic temperatures to achieve good energy resolution. We propose to develop an innovative, miniature cryogenic cooling system that will be ideal for hand-held detectors. High efficiency will enable long battery life, and low vibration will improve detector sensitivity. The system will be lightweight and inexpensive to produce. In Phase I, we have proven the feasibility of our approach by building and demonstrating critical components and producing a conceptual design for a prototype cryocooler. In Phase II, we will build and demonstrate a complete prototype cryocooler and integrate it with a hand-held gamma ray spectrometer. Tests of the cryocooler will demonstrate high cooling efficiency, and tests of the cooled spectrometer will demonstrate excellent detector performance. Homeland security applications include nuclear materials interdiction, safeguards inspection, and emergency response. The cooler can also be used to cool portable x-ray detectors and infrared sensors used in military targeting and guidance systems. The commercial nuclear industry can use the cooler/detector for in-situ waste assay measurements, nuclear reactor maintenance, and health physics.

H-SB05.1-004

Company

FarSounder, Inc.
43 Jefferson Blvd.
Warwick, RI 02888-1078

Proposal Information 0512013 - Low Cost 3D Sonar System for Underwater Threat Detection
Topic Information H-SB05.1-004 - LOW COST UNDERWATER THREAT DETECTION SYSTEM
Award/Contract Number NBCHC060087
Abstract

FarSounder proposes to develop a low cost 3D sonar system for underwater threat detection. This system will be based on the design and feasibility study developed during the recently completed Phase I SBIR. FarSounder has developed this solution concept with effective performance and end usability in mind, using FarSounder 3D sonar technology and a hardware architecture that utilizes COTS components thereby ensuring affordable future product costs. This approach will leverage FarSounder`s advanced processing techniques to increase the system`s performance when compared to currently available port security sonars. Through simulation, field testing with existing hardware and acoustic modeling, FarSounder has already validated the key elements of the design. For this Phase II effort FarSounder will design and build a prototype low cost, low power, small size system for incorporation into a multi-faceted Port Security System. The ultimate commercialized system will be easy to use, easy to deploy, have a low false alarm and fall within the goal of less than $100K per 1000 feet of protected asset. This system will have the ability to detect open circuit divers, closed circuit divers, divers with propulsion assistance and underwater vehicles that approach or enter the security zone and provide an alert to a central station or system operator. FarSounder`s solution will have a high probability of detection of real underwater threats and a low false alarm rate for these targets. Benefits include increased protection of ports, critical waterside infrastructures and other fixed shoreline sites and prevention of attacks affecting large areas of local populations such as those near LNG terminals. The system will provide the first underwater port security system practical for use in all US ports and along extensive areas of US coastlines and inland waterways. Spinoff commercial applications include a solution for the protection of endangered marine mammals, by enabling effective localization, identification and avoidance of these mammals; a cost efficient localization and identification sonar appropriate for the $3.2B annual US fisheries industry to reduce by-catch; and a low-cost on-board security sonar system for commercial cargo ships, oil tankers, passenger vessels and large recreational boats.

Company

BioSonics, Inc.
4027 Leary Way NW
Seattle, WA 98107-5045

Proposal Information 0512015 - Phase II: The BioSonics UnderWater ACoustic Sentinel (UWACS), a Low Cost Underwater Threat Detection System
Topic Information H-SB05.1-004 - LOW COST UNDERWATER THREAT DETECTION SYSTEM
Award/Contract Number D06PC75600 (formerly NBCHC060092)
Abstract

The purpose of this Phase II project is to develop, build and test a fully functional, multi-node UnderWater ACoustic Sentinel (UWACS) production prototype system for homeland security applications. The UWACS system is intended to detect and classify divers (and other human intruders) underwater and on the surface in harbors, ports, and other waterside sites susceptible to such intrusion. BioSonics has been an industry leader in the field of sonar for fisheries and underwater habitat assessment for 28 years. In Phase I, BioSonics succeeded in developing, building and field testing a research prototype UWACS active acoustic system, capable of detecting, locating and tracking underwater swimmers and surface craft at ranges greater than 300 meters in complex, shallow, saltwater environments. In Phase II, the UWACS research prototype system will be enhanced to support multiple networked scanning acoustic nodes, simultaneously providing data to the master control unit to allow adaptive wide sector coverage. BioSonics will develop a user friendly Graphic User Interface (GUI) to enable complete system configuration capability, surveillance sector visualization, target assessment and localization. System data output protocols will be industry compatible. The commercialization potential of the BioSonics UWACS system for homeland security, defense, public and private sector markets is tremendous.

Company

Acoustech Corporation
Philadelphia Naval Business Center
4900 South Broad Street, Building 6, Suite LL00
Philadelphia, PA 19112-1302

Proposal Information 0512017 - LOW COST UNDERWATER THREAT DETECTION SYSTEM
Topic Information H-SB05.1-004 - LOW COST UNDERWATER THREAT DETECTION SYSTEM
Award/Contract Number NBCHC070008
Abstract

Acoustech Corporation, Applied Physical Sciences Corporation, and Navmar Applied Sciences Corporation have teamed to develop a low cost surveillance system that will protect assets located along the shoreline from domestic and foreign terrorists. The surveillance system consists of a multistatic sonar system and a passive optical/thermal imaging system. The Phase II project is centered on advanced development of the systems and components that were developed during Phase I. Key areas of R&DTE include development of acoustic transducers, data acquisition modules, and telemetry; development of signal processing algorithms to detect, classify, and localize targets; and performing tasks related to systems integration. A full scale experiment is planned to evaluate the performance of the surveillance system in which divers and swimmers will be used as targets in a predetermined security zone spanning 1,000 ft of shoreline in a realistic saltwater environment. A comprehensive commercialization plan will be developed and implemented concurrent with the technical agenda of the Phase II effort.

H-SB05.1-005

Company

Lynntech, Inc.
2501 Earl Rudder Freeway South
College Station, TX 77845-6023

Proposal Information 0512002 - A Non-Lethal, Non-Tethered, Inexpensive Electro-Muscular Disruption Projectile
Topic Information H-SB05.1-005 - INNOVATIVE LESS-LETHAL DEVICES FOR LAW ENFORCEMENT
Award/Contract Number NBCHC070014
Abstract

Recent trends in law enforcement clearly illustrate the effectiveness of the taser to debilitate even the toughest targets without causing permanent injury or lingering after-effects. Current electric stun technology is either hand-held or short-range and tethered to the launch platform. Law enforcement agencies would benefit from longer range, non-tethered electric stun projectiles. The introduction of tasers caused sharp decreases in injuries to both police officers and suspects and the same is expected for long range electro-muscular disruption (EMD) devices. During the Phase I project Lynntech designed and demonstrated a 40 mm non-lethal, non-tethered, EMD projectile with a wireless "tase on demand" capability. During the Phase II project, Lynntech will modify the 40 mm to a dual 37 (40) mm round for greater applicability, develop a standard 12 gauge EMD round, demonstrate a forty meter range for both, determine the optimal price point for both, and fabricate several marketable prototypes of each. Additionally, Lynntech will identify the required human effects testing. The two primary customers are the military and law enforcement agencies. Other potential users include customs and border patrol agents, security personnel at airports, banks, and private organizations, animal control agencies, zoos, and everyday citizens seeking personal and property protection.

Company

Intelligent Optical Systems, Inc.
2520 W. 237th Street
Torrance, CA 90505-5217

Proposal Information 0512003 - Less-Lethal Eye Safe Handheld LED-Based Incapacitator for Law Enforcement
Topic Information H-SB05.1-005 - INNOVATIVE LESS-LETHAL DEVICES FOR LAW ENFORCEMENT
Award/Contract Number NBCHC060081
Abstract

In Phase I, Intelligent Optical Systems (IOS) developed and demonstrated a hand-held, battery operated prototype nonlethal weapon that utilizes an array of super-bright light emitting diodes (LEDs) to produce flashing light that causes disorientation and flashblindness in the target subject(s). To enhance the effectiveness of the LED-based Incapacitator (LEDI), IOS incorporated and evaluated such supplementary features as multiple colors, random and periodically changing frequencies and intensities of light, an embedded flashlight, a multidirectional strobe, and an ultrasonic rangefinder, which provides eye-safe operation. IOS also outlined, by establishing the preliminary calculations for narrow beam forming optics and a powerful die cluster on a single substrate, the development of a device that will operate at power levels close to the eye-damage threshold, yet in hand-held format. In Phase II, IOS will develop and fabricate a LEDI, and tests will be performed on human subjects. The final Phase II LEDI prototype will operate at the eye-damage threshold at distances up to 21-25 feet, and produce strong flashblindness with afterimages at distances up to 50 feet. The LEDI is intended to serve as a complementary supportive weapon for the nonlethal Tazer and other more lethal equipment of military and security personnel.

Company

Mide Technology Corporation
200 Boston Avenue Suite 1000
Medford, MA 02155-4242

Proposal Information 0512004 - Untethered Electro-Muscular Disruption Round
Topic Information H-SB05.1-005 - INNOVATIVE LESS-LETHAL DEVICES FOR LAW ENFORCEMENT
Award/Contract Number NBCHC070002
Abstract

Mide is proposing to develop and demonstrate an untethered electro-muscular disruption non-lethal stun round for civil law enforcement officers and the military. The innovative device will provide individual threat control at increased range (15 - 50 meters) over existing weapons and it will be compatible with 12-gauge shotguns. The device combines the proven effectiveness, legal and social acceptability of the current tethered EMD devices with the ease of use, practicality, and extended range of shotgun shells. Utility of the innovation is probably best realized in crowd control situations or riots having high levels of aggression. The major benefits of the innovation is that the untethered round avoids all the problems associated with tethered wires, snagging and breaking of the wires, resistive losses and inaccurate delivery of the barbs. While Phase I established a feasible preliminary design, Phase II will further optimize the design and validate though engineering tests the performance of the round. Real scale round will be fired to ensure accuracy and safety. Additional physiological performance tests will also be performed as needed. If funded, the effort will provide a timely non-lethal round that will help to safe lives and protect our people and security forces.

H-SB05.1-006

Company

Physical Optics Corporation
20600 Gramercy Place, Building 100
Torrance, CA 90501-1821

Proposal Information 0512009 - Secure Carton Integrated Electronic Remote System
Topic Information H-SB05.1-006 - SECURE CARTON SYSTEM
Award/Contract Number NBCHC060086
Abstract

To address the Department of Homeland Security need for a novel secure carton integrated with intermodal ISO containers, and the Advanced Container Security Device, Physical Optics Corporation (POC) has developed a novel "carton-centric" Secure Parcel ISO Distributed Enhanced RFID (SPIDER), which will enhance container-based ACSD and RFID tags with a low false alarm rate, responding to a broad variety of security scenarios to protect against sophisticated carton intrusion. The three-security-layer SPIDER architecture includes: smart skin, wireless status reporting, and authentication and ID. The smart skin is based on a unique, X-ray-transparent concealed electrical cage. The system can be entirely passive, inductively drawing power from the container RFID. Most of the technology for SPIDER mass production is well established. In Phase I, two generations of working prototypes were developed, fabricated, and demonstrated to DHS and to an Under Secretary of Defense. In Phase II we will extend the SPIDER concept to two protective network meshes: one similar to that of Phase I, and a new one with stretching capability to dramatically improve false alarm rate. SPIDER will find applications in cargo screening, container inspection, and special-purpose packages for sensitive items: pharmaceuticals, electronic chips, weapons, and classified materials.